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dc.contributor.authorÇakıcı, Musa
dc.contributor.authorDoğan, Adnan
dc.contributor.authorÇetin, Mustafa
dc.contributor.authorSüner, Arif
dc.contributor.authorPolat, Mustafa
dc.contributor.authorOylumlu, Muhammed
dc.contributor.authorAktürk, Erdal
dc.contributor.authorAbus, Sabri
dc.contributor.authorÜçkardeş, Fatih
dc.description.abstractObjective: The coronary sinus (CS) has been largely ignored by physicians due to a lack of adequate data about the importance of CS enlargement in patients with heart failure (HF). We aimed to assess whether CS dilatation develops in patients with HF and to demonstrate its relation with global myocardial function of the right ventricle (RV). Methods: In this cross-sectional study, 45 healthy subjects and 95 HF patients exhibiting left ventricular systolic dysfunction on echocardiographic examination (EF <45%) secondary to ischemic (n=56) or idiopathic dilated cardiomyopathy (DCM) (n=39) were enrolled. Patients with severe renal dysfunction and/or valve disease were excluded. CS was measured by echocardiography from the posterior atrioventricular groove in the apical four-chamber view. The RV myocardial performance index (MPI), which reflects both systolic and diastolic function of the ventricle, was detected using tissue Doppler imaging, and patients with an RV MPI >0.55 were defined as having impaired RV myocardial function. ANOVA, Kruskal-Wallis, Pearson’s correlation, and multivariate logistic regression analyses were used for the statistical analysis. Results: The CS and RV MPI values were significantly greater both in patients with ischemic and idiopathic DCM than in controls (8.79±1.7 mm and 8.33±2.1 mm vs. 5.74±0.6 mm, and 0.64±0.07 and 0.62±0.08 vs. 0.43±0.02; p<0.001 for both, respectively). For the prediction of HF patients with impaired RV function, the cut-off value for the diameter of the CS was 7.35 mm, with a sensitivity of 83% and a specificity of 79%. Conclusion: The CS diameter can be used as a novel echocardiographic marker that provides information about impaired RV function in patients with HF. (Anatol J Cardiol 2015; 15: 542-7)en_US
dc.subjectKalp ve Kalp Damar Sistemien_US
dc.subjectCoronary Sinusen_us
dc.subjectRight Ventricleen_us
dc.subjectMyocardial Performance İndexen_us
dc.subjectHeart Failureen_us
dc.titleCoronary sinus dilatation is a sign of impaired right ventricular function in patients with heart failureen_US
dc.relation.journalThe Anatolian Journal of Cardiologyen_US
dc.departmentKütahya Dumlupınar Üniversitesien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]

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